Preterm Birth

What is Preterm Birth?

Pregnancy normally lasts about 40 weeks (a little over 9 months since the start of the last period). “Preterm birth” is defined as birth before 37 weeks of pregnancy. It can happen on its own, which is called spontaneous preterm birth. It can also happen when labor is induced (started by drugs or other means) or a cesarean delivery is performed early for a medical reason to protect the mother or baby’s health. This is called a medically indicated preterm birth.

Preterm birth has been divided into these categories:

  • Preterm: Birth that occurs before 37 weeks of pregnancy

  • Late preterm birth: Birth that occurs between 34 and 36 weeks of pregnancy

  • Early preterm birth: Birth that occurs before 34 weeks of pregnancy

The earlier a baby is born, the greater the chance for more serious and long-lasting health risks. But even babies born later in the preterm period (between 34 and 36 weeks) can have health problems. Babies born before 23 weeks rarely survive.


How common is preterm birth?

About 1 in 10 babies in the United States is born preterm.

How can being born preterm affect my baby’s health?

Infants born preterm are more likely to have health problems, especially during the first year of life. These include:

  • Problems with breathing, eating, and keeping warm

  • Infections

  • Movement and coordination problems

  • Hearing and vision loss

  • Slower growth and development compared to peers

  • Behavioral problems and learning difficulties

Preterm babies may need to stay in a neonatal intensive care unit (NICU) to get special medical care. Once they leave the hospital, some babies need ongoing care to treat medical issues. Sometimes these problems last well into childhood.

What are the risk factors for or causes of preterm birth?

The following risk factors have been associated with preterm birth:

  • Preterm birth in a previous pregnancy

  • Lifestyle factors, including smoking, substance use, and low prepregnancy weight

  • Having a lower income, living in a poorer area or neighborhood, and lack of access to prenatal care

  • Getting pregnant less than 18 months after having a baby

  • Having bacteria in the urine, a condition called bacteriuria, especially if it occurs without causing any symptoms

  • Having a short cervix as measured by ultrasound

  • Pregnancy complications such as preeclampsia, problems with the placenta, fetal growth restriction, and fetal genetic conditions

  • Medical problems that existed before pregnancy, including high blood pressure, diabetes, and lupus

  • Preterm labor (when labor contractions start too early) and premature rupture of membranes (when your water breaks before labor starts and it’s before 37 weeks)

  • Being pregnant with twins, triplets, or more

Many pregnant people have at least 1 risk factor for preterm birth. Having a risk factor does not mean that you will have a preterm birth. Some risk factors, like smoking, can be changed. Others cannot be changed, such as having a previous preterm birth, but extra care during pregnancy may be recommended.

What are the signs and symptoms of preterm labor?

  • Frequent, regular contractions that:

    • Occur 6 or more times in 1 hour

    • Cause your belly to tighten and harden and are uncomfortable

  • Lower abdominal cramps or a low backache that gets worse or doesn’t go away

  • A change in vaginal discharge (watery, bloody, or like mucous) or an increase in discharge

  • Pelvic pressure (a feeling that the baby is pushing down)

  • Your water breaks

  • Bleeding with or without abdominal pain

What should I do if I have signs and symptoms of preterm labor?

If you have mild signs or symptoms, contact your healthcare provider right away. If your symptoms are severe or getting worse, you should go to the nearest hospital if you can do so safely. If you are worried about your safety or have heavy bleeding, call emergency services (911).   

How is preterm labor managed?

Sometimes preterm labor stops on its own. How your symptoms will be managed depends on your signs and symptoms, how far along you are (gestational age), and whether your cervix has started to open (dilate) or soften. 

  • You will likely be admitted to the hospital. In some cases, you may be transferred to a hospital that can care for very preterm infants.

  • A steroid medication may be given to prepare the fetus’s lungs and other organs for a possible early birth.  

  • If you are less than 32 weeks pregnant, another medication called magnesium sulfate may be given to protect the fetal brain and nervous system. This medication has been shown to reduce rates of cerebral palsy and death in babies who are born before 32 weeks.   

  • You may receive medications called tocolytics to try to slow down contractions. This gives time for the steroid injections or magnesium sulfate to take effect or for you to be moved to a hospital with a higher level of care.  

Can anything be done to prevent preterm birth?

Preterm birth prevention can start even before you become pregnant. Your healthcare provider can help you address any risk factors that could be changed, like stopping smoking or getting better nutrition.

During an early prenatal care visit, you will have a test to see if you have bacteria in your urine. The length of your cervix may be measured at the standard ultrasound exam between 18 and 23 weeks of pregnancy. If you are found to have a short cervix, treatment with vaginal progesterone may be recommended. This treatment has been shown to reduce the risk of preterm birth. This medication is also offered to people who have had a prior spontaneous preterm birth.

In some cases,  a procedure called cerclage may be recommended. In this procedure, a stitch is placed around the cervix to hold it closed. It is most often done through the vagina or, less frequently, with laparoscopy through the abdomen. With the abdominal approach, a cesarean delivery is needed. The approach used depends on many factors, such as how far along you are in pregnancy, your personal history of preterm birth or miscarriage, and the experience of your healthcare provider.

Braxton-Hicks contractions are “practice” contractions that you may notice starting in the second trimester of pregnancy. They differ from real labor pains in the following ways:

Braxton-Hicks: Unpredictable; feel like mild abdominal cramps or tightening; infrequent; get better if you change position or drink water

Real labor: Occur regularly; are painful; get stronger and more frequent; don’t get better with position change

If you have any doubts about what you are feeling, it’s best to contact your healthcare provider to be sure.

Quick Facts

  • “Preterm birth” is defined as birth before 37 weeks of pregnancy.

  • Infants born preterm are more likely to have health problems, especially during the first year of life. The earlier a baby is born, the greater the chance for more serious and long-lasting health risks.

  • Risk factors for preterm birth include a previous preterm delivery; lifestyle factors such as smoking, and having a short cervix. Many pregnant people have at least 1 risk factor for preterm birth. Having a risk factor does not mean that you will have a preterm birth.

  • Signs of preterm birth include frequent, regular contractions; lower abdominal cramps or a low backache; a change or increase in vaginal discharge; pelvic pressure; water breaking; and bleeding with or without abdominal pain.

  • Preterm labor may stop on its own. If it doesn’t, sometimes medications are used to slow contractions. If it looks like birth will happen, medications to help the fetus’s organs mature and protect the fetal brain from damage can be given in some cases.

Glossary

Bacteriuria: The presence of bacteria in the urine.

Braxton-Hicks contractions: “Practice” contractions that can occur in the second trimester of pregnancy.

Cerclage: A procedure in which a stitch is placed around the cervix to attempt to hold it closed to prevent or delay preterm birth.

Cerebral Palsy: A disorder caused by abnormal brain damage or development that may occur before or at birth. It results in problems with balance, posture, and movement.

Cesarean Delivery: Surgery in which a baby is delivered through a cut (incision) in the uterus.

Fetal Growth Restriction: A condition in which a fetus measures much smaller than expected for the gestational age.

Gestational Age: The age of a pregnancy, usually given in weeks. A pregnancy is dated from the first day of the last menstrual period. The standard length of pregnancy is 40 weeks.

Laparoscopy: A type of surgery in which the surgeon looks inside the body with a slender camera and performs surgery with special instruments inserted through small incisions. Also called “minimally invasive surgery.”

Magnesium Sulfate: A medication that helps the fetal brain and nervous system mature and reduces the risk of cerebral palsy in the event of a possible preterm birth.

Medically Indicated Preterm Birth: Inducing labor or performing a cesarean delivery early to protect the mother or baby’s health. 

Placenta: A special organ made by the body during pregnancy. It allows the transfer of nutrients, antibodies, and oxygen to the fetus from the woman. It also makes hormones that sustain the pregnancy. 

Preeclampsia: A disorder that can occur during pregnancy in which the blood pressure gets too high. It can damage many organs in the body, including the kidneys, brain, and liver.

Progesterone: A hormone that regulates the menstrual cycle and plays a role in pregnancy. It is also used as a medication.  

Preterm: Delivery of a baby before 37 weeks of pregnancy.

Spontaneous Preterm Birth: A preterm birth that occurs on its own.

Steroid: A type of medication that can help the fetal lungs and other organs mature in preparation for a possible preterm birth.