Tdap Vaccine During Pregnancy

Tdap is the vaccine that protects adults against pertussis.


What is pertussis?

Pertussis is a disease caused by bacteria. It starts with cold-like symptoms and then causes a bad cough. Coughing fits can be so severe that it can be hard to catch your breath. You may make a whooping sound as you try to get air.

Pertussis is very contagious. It is easily spread through the air when infected people cough.

Babies, especially those younger than 1 year, can become very sick if they get pertussis. Instead of coughing, they may gasp, gag, or throw up. They can turn blue from lack of oxygen. Apnea (when a baby stops breathing for a short time) and seizures may occur.

Some babies get pneumonia as a result of having pertussis. One-half need to go to the hospital. In the United States, a small number of infants die each year from pertussis.

What vaccines are available to prevent pertussis?

There are two vaccines for pertussis that are given at different ages and life situations:

DTaP is given to babies and children. It protects against pertussis and two other serious diseases, tetanus and diphtheria. Babies get their first dose of DTaP at age 2 months, and then 4 more doses at ages 4 months, 6 months, 15–18 months, and 4–6 years.

A booster shot, called Tdap, is given at age 11–12 years.

Adults older than age 19 who have never had Tdap should get it once during their lifetime. It can replace one of the tetanus booster shots (Td) that is given every 10 years.

Pregnant women need to get Tdap during each pregnancy.

Why is getting vaccinated against pertussis with Tdap important during pregnancy?

Babies can’t be vaccinated until they are 2 months old. They aren’t protected against pertussis until they can get the vaccine. You can help protect your baby during this time by getting the vaccine during pregnancy.

Why do I need to get Tdap during each pregnancy?

When you get Tdap, your body immediately starts making antibodies. These are the proteins made by your immune system that target pertussis if you are exposed to it.

These antibodies cross the placenta and enter your fetus’s bloodstream. When your baby is born, he or she will have enough antibodies to protect against pertussis until it’s time to get the vaccine at age 2 months. Getting Tdap during every pregnancy boosts your antibodies so that the maximum amount can be transferred to your fetus.

When should I get Tdap during pregnancy?

The best time to get Tdap is between 27 and 36 weeks of pregnancy. It’s recommended that you get it as early as possible within this timeframe.

What if I don’t get Tdap during my pregnancy?

You can get Tdap after pregnancy. Breastfeeding will transfer the antibodies you make after getting the vaccine to your baby. But it takes up to 2 weeks for your body to make the maximum amount of antibodies. During this time, your baby may not be fully protected against pertussis. That’s why the best way to protect your baby is to get Tdap during each pregnancy.

Is the vaccine safe during pregnancy?

Yes. Tdap vaccination in pregnancy is very safe. Research done in the last 10 years has shown that getting the vaccine during pregnancy doesn’t increase the risk of pregnancy problems or birth defects.

Who else in the household should get a Tdap vaccine?

All family members and caregivers who will have contact with your baby should also have had a Tdap booster vaccine. Even if they received a standard tetanus booster within the past 10 years, they should get the Tdap vaccination at least 2 to 3 weeks before the baby is born.

Are there side effects of the Tdap vaccine?

The vaccine has very few side effects. Pain and redness can occur where the injection is given. If any pain, redness, or swelling lasts beyond a few days, contact your health-care provider

Quick Facts About Tdap During Pregnancy

  • Pertussis is a contagious disease that causes a bad cough.

  • In babies, it can be very serious. One-half of babies who get pertussis end up in the hospital.

  • There is a vaccine for pertussis, but babies can’t get it until they are 2 months old. You can protect your newborn by getting vaccinated with the pertussis vaccine (Tdap) when you are pregnant.

  • To give your baby the best protection, you need to get Tdap during each pregnancy. The ideal time is between 27 and 36 weeks of pregnancy.

  • Tdap has been proven to be safe during pregnancy. It does not cause birth defects or pregnancy problems.

 

References

CDC. 5 Facts about Tdap and Pregnancy. https://www.cdc.gov/vaccines/pregnancy/hcp-toolkit/tdap-vaccine-pregnancy.html. Accessed June 5, 2023.

 CDC. Get a Whooping Cough Vaccine During Each Pregnancy. https://www.cdc.gov/pertussis/pregnant/mom/get-vaccinated.html. Accessed June 5, 2023.

 CDC. Getting Tdap during pregnancy passes protection to baby. https://www.cdc.gov/pertussis/pregnant/mom/get-vaccinated.html#:~:text=Getting%20Tdap%20between%2027%20through,along%20with%20getting%20whooping%20cough Accessed June 5, 2023.

  Hill HA, Elam-Evans LD, Yankey D, Singleton JA, Dietz V. Vaccination Coverage Among Children Aged 19–35 Months — United States, 2015. MMWR Morb Mortal Wkly Rep 2016;65:1065–1071. DOI: http://dx.doi.org/10.15585/mmwr.mm6539a4external icon.

 Murphy TV, Slade BA, Broder KR, et al. Prevention of pertussis, tetanus, and diphtheria among pregnant and postpartum women and their infants recommendations of the Advisory Committee on Immunization Practices (ACIP) [published correction appears in MMWR Morb Mortal Wkly Rep. 2008 Jul 4;57(26):723]. MMWR Recomm Rep. 2008;57(RR-4):1-51.

Last update: July 28, 2023